IMPACT FACTOR: 1.2
Epithelioid Sarcoma (ES) of the vulva is a rare and an aggressive malignant soft tissue neoplasm. It is classified into distal, conventional (classic), and proximal types. Presence of morphologic and immunehistochemichal markers of yolk-sac differentiation may represent morphologic variants of SMARCB1-deficient tumors rather than primary vulvar germ cell neoplasia.
A cesarean scar pregnancy is a rare entity for which there is no consensus on the preferred mode of treatment. We present a case of a 20s woman who presented with profuse vaginal bleeding in the context of a cesarean section pregnancy.
Approximately 1-1.5 people per million will develop the rare coagulopathy of acquired hemophilia A. This autoantibody-mediated destruction of Factor VIII and can lead to severe hemorrhage. Here we describe a first presentation of an acquired hemophilia A in an 89 year old female who had recently undergone hysteroscopic surgery, and presented with transfusion-dependent anemia. We review the workup, diagnosis, and multidisciplinary management of this rare but potentially life-threatening condition.
Necrotizing Fasciitis (NF) is an aggressive, rapidly progressing and life-threatening infection characterized by spreading necrosis of subcutaneous tissue and fascia. NF of the breast is a very rare entity. We present a case of NF of the breast occured in a 22-year-old breastfeeding woman after topical application of traditional herbal medicine.
Nephrolithiasis is a chronic metabolic disease characterized by a number of physical and chemical processes including supersaturation, nucleation, development, aggregation, and retention of urinary calculi components inside the tubular cells.
A 21-year-old Iranian female presented to hospital with irregular menstruation, heavy menstrual bleeding and severe secondary dysmenorrhea for three years with a history of primary amenorrhea was referred to genecology oncology section.
A 63-year-old female was found to have an ovarian tumour during workup for microscopic hematuria. Histologic analysis after bilateral salpingo-oophorectomy revealed a borderline clear cell adenofibroma with focal microinvasion and associated granulosa cell tumour. There was no adjuvant chemotherapy or radiation therapy. Borderline clear cell carcinomas alone are rare and no cases of combined clear cell borderline tumour with granulosa cell tumour have been described in the literature to our knowledge. Review of evidence for treatment of each tumour alone suggests surgical excision as primary treatment, but recurrence rates of a combined tumour such as this are not known so long-term follow-up cannot be excluded
Müllerian agenesis, Mayer-Rokitansky-Küster-Hauser Syndrome (MRKH), or vaginal agenesis, has an incidence of 1 per 4,500–5,000 females. It is caused by embryologic underdevelopment of the Müllerian duct, causing agenesis or atresia of the vagina, uterus, or both [1].
This case reviews a unique course of a 39-year-old pregnant woman presenting on second trimester with an uncommon combination of vomiting, hypovolemic shock, pancreatitis and thyrotoxicosis. In this case report, we discuss a few possible explanations of presenting illness, including pregnancy-related and unrelated causes, with a possibility that a combination of some of these causes could have led the complete picture. We hope this study will contribute to the understanding of the causes and possible outcomes of acute and severe illnesses presenting during pregnancy.
To present 4 case of chemo-resistant Gestational Trophoblastic Neoplasms (GTN) who were treated with local myometrial resection with uterine reconstruction as a fertility-preserving surgery.
Since the broad ligament is closely related to other structures, such as the uterus, fallopian tubes, and ovaries, secondary involvement of it due to primary malignancy elsewhere is common. Primary broad ligament malignancies are rare. Only 29 cases of primary broad ligament malignancies have been reported in the literature, out of which only 5 cases of endometrioid adenocarcinoma.
Madam C was a 39-year-old primiparous lady having history of one IVF pregnancy delivered by Caesarean section (CS). She was found cervical intra-epithelial neoplasia (CIN) 2-3 with loop electro-excision procedure (LEEP) performed 6 months after her delivery while she was still breastfeeding. 1.8cm-thick, 2cm-wide cervix was resected and diagnosed CIN 1.
Rupture of haemorrhagic corpus luteum is a common cause of hemoperitoneum in women of reproductive age. In rare cases, it can represent the first manifestation of a haemato-oncologic disease. Here we present the case of a 24-year-old woman with acute abdomen due to haemorrhagic corpus luteum hemoperitoneum as the first manifestation of acute myeloid leukaemia.
Elevated levels of CA19.9 is usually associated with malignancies of the hepatobiliary and the pancreatic system. It not only helps to diagnose the malignancy, but also very high levels can indicate advanced or metastatic diseases [1].
However in rare instances elevated CA19.9 has been found in patients with adnexal masses. This is not only uncommon but also confounding, while trying to ascertain the nature of the ovarian mass and to determine the optimal surgical management in young and premenopausal patients.
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