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Para-Vulvar Proximal Epithelioid Sarcoma (ES) with Yolk Sac Differentiation: A Case Report

Reda Hemida*; Amany A Makroum; Sylvia Albair; Mohammad Hasan; Ghada Eladawei; Fatma MF Akl; Shimaa Elmetwally; Rafik Barakat; Adel Helal; Emad Feyala

    Epithelioid Sarcoma (ES) of the vulva is a rare and an aggressive malignant soft tissue neoplasm. It is classified into distal, conventional (classic), and proximal types. Presence of morphologic and immunehistochemichal markers of yolk-sac differentiation may represent morphologic variants of SMARCB1-deficient tumors rather than primary vulvar germ cell neoplasia.


Consecutive Failed Treatment Approaches in a Cesarean Scar Ectopic Pregnancy-placental Accretism Sprectrum

Carolina Carneiro*

   A cesarean scar pregnancy is a rare entity for which there is no consensus on the preferred mode of treatment. We present a case of a 20s woman who presented with profuse vaginal bleeding in the context of a cesarean section pregnancy.


Beyond the Uterus: An Unusual Cause of Transfusion-Dependent Vaginal Bleeding

Rebecca Manion*

   Approximately 1-1.5 people per million will develop the rare coagulopathy of acquired hemophilia A. This autoantibody-mediated destruction of Factor VIII and can lead to severe hemorrhage. Here we describe a first presentation of an acquired hemophilia A in an 89 year old female who had recently undergone hysteroscopic surgery, and presented with transfusion-dependent anemia. We review the workup, diagnosis, and multidisciplinary management of this rare but potentially life-threatening condition.


Necrotizing Fasciitis of the Breast after Topical Application of Traditionnal Herbal Medecine: A Case Repor

Ulrich Igor Mbessoh Kengne*; Mamadou Ndiaye; Mame Diarra Bousso Ba; Amacoumba Fall; Esaie Kasokota Kamona; Mamadou Sow; Mohamed Ezzet Charfi; Jaafar Ibn Abou Talib; Sidy Ka; Ahmadou Dem

   Necrotizing Fasciitis (NF) is an aggressive, rapidly progressing and life-threatening infection characterized by spreading necrosis of subcutaneous tissue and fascia. NF of the breast is a very rare entity. We present a case of NF of the breast occured in a 22-year-old breastfeeding woman after topical application of traditional herbal medicine.


Post-Menopausal Consequences in Nephrolithiasis

Smriti; Saurabh Sharma*

    Nephrolithiasis is a chronic metabolic disease characterized by a number of physical and chemical processes including supersaturation, nucleation, development, aggregation, and retention of urinary calculi components inside the tubular cells.


Non-gestational Ovarian Choriocarcinoma in a Virgin Woman: A Case-Report

Vahid Kaveh; Soheila Aminimoghaddam*; Mobina Yarahmadi; Mohammadhossein Vazirizadeh-Mahabadi

    A 21-year-old Iranian female presented to hospital with irregular menstruation, heavy menstrual bleeding and severe secondary dysmenorrhea for three years with a history of primary amenorrhea was referred to genecology oncology section.


A Case of Ovarian Borderline Clear Cell Adenofibroma with Associated Granulosa Cell Tumour

Jack Heard; Mathieu Viau; Gabor Fischer; Nazila Azordegan; Gary Keeney; Alon D Altman*

    A 63-year-old female was found to have an ovarian tumour during workup for microscopic hematuria. Histologic analysis after bilateral salpingo-oophorectomy revealed a borderline clear cell adenofibroma with focal microinvasion and associated granulosa cell tumour. There was no adjuvant chemotherapy or radiation therapy. Borderline clear cell carcinomas alone are rare and no cases of combined clear cell borderline tumour with granulosa cell tumour have been described in the literature to our knowledge. Review of evidence for treatment of each tumour alone suggests surgical excision as primary treatment, but recurrence rates of a combined tumour such as this are not known so long-term follow-up cannot be excluded


Successful Treatment of Rare Disorder Mayer-Rokitansky-Küster-Hauser Syndrome: 3 Years Follow Up And Reproductive Outcome Case Report

Tamaz Nikolaishvili; David Gagua; Tinatin Gagua*; Beka Metreveli; Aleksandra Gvenetadze

    Müllerian agenesis, Mayer-Rokitansky-Küster-Hauser Syndrome (MRKH), or vaginal agenesis, has an incidence of 1 per 4,500–5,000 females. It is caused by embryologic underdevelopment of the Müllerian duct, causing agenesis or atresia of the vagina, uterus, or both [1].


Acute Pancreatitis in a Pregnant Woman Complicated by Hypovolemic Shock: A Case Report and Literature Review

Efrat Miskin; Tamar Eshkoli; Elena Korytnikova*; Ofir Almasi; Leonid Barski

    This case reviews a unique course of a 39-year-old pregnant woman presenting on second trimester with an uncommon combination of vomiting, hypovolemic shock, pancreatitis and thyrotoxicosis. In this case report, we discuss a few possible explanations of presenting illness, including pregnancy-related and unrelated causes, with a possibility that a combination of some of these causes could have led the complete picture. We hope this study will contribute to the understanding of the causes and possible outcomes of acute and severe illnesses presenting during pregnancy.


Local Myometrial Resection for Chemo-Resistant Gestational Trophoblastic Neoplasia: Case Series and a Surgical Video

Reda Hemida*; Emad Fyala; Ahmed Ragab; Hesham Abu-Taleb

    To present 4 case of chemo-resistant Gestational Trophoblastic Neoplasms (GTN) who were treated with local myometrial resection with uterine reconstruction as a fertility-preserving surgery.


Primary Broad Ligament Endometroid Adenocarcinoma: A Case Report and Review of Literature

Sunita Gupta*; Savita Malik; Balaji Balasubramaniam; Priya Shambhukumar

    Since the broad ligament is closely related to other structures, such as the uterus, fallopian tubes, and ovaries, secondary involvement of it due to primary malignancy elsewhere is common. Primary broad ligament malignancies are rare. Only 29 cases of primary broad ligament malignancies have been reported in the literature, out of which only 5 cases of endometrioid adenocarcinoma.


Management of Cervical Stenosis - Mechanical Dilatation Adjunct with Hormonal Therapy

Wong Pui Ying*; Yu Chun Hung

    Madam C was a 39-year-old primiparous lady having history of one IVF pregnancy delivered by Caesarean section (CS). She was found cervical intra-epithelial neoplasia (CIN) 2-3 with loop electro-excision procedure (LEEP) performed 6 months after her delivery while she was still breastfeeding. 1.8cm-thick, 2cm-wide cervix was resected and diagnosed CIN 1.


Acute Myeloid Leukaemia Presenting as Ruptured Haemorrhagic Corpus Luteum

Nikita Alfieri; Sara Charlotte Simonetti*; Anna Maria Marconi; Giorgia Gaia

    Rupture of haemorrhagic corpus luteum is a common cause of hemoperitoneum in women of reproductive age. In rare cases, it can represent the first manifestation of a haemato-oncologic disease. Here we present the case of a 24-year-old woman with acute abdomen due to haemorrhagic corpus luteum hemoperitoneum as the first manifestation of acute myeloid leukaemia.


Unusually Elevated CA19.9 With Adnexal Mass: Does it Lead to Some Conclusions or Confusion?

M D Ray*; Pallabika Mandal

    Elevated levels of CA19.9 is usually associated with malignancies of the hepatobiliary and the pancreatic system. It not only helps to diagnose the malignancy, but also very high levels can indicate advanced or metastatic diseases [1].
However in rare instances elevated CA19.9 has been found in patients with adnexal masses. This is not only uncommon but also confounding, while trying to ascertain the nature of the ovarian mass and to determine the optimal surgical management in young and premenopausal patients.


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