IMPACT FACTOR: 1.8
The purpose of this clinical study was to use rigorous clinical criteria to diagnose Meibomian Gland Dysfunction (MGD) and perform meibography to evaluate differences in meibomian gland structure compared with non-MGD participants. A prospective, non-interventional, multi-center, clinical study included 3 cohorts (i.e. non-MGD, mild/moderate MGD, and severe MGD) classified using composite criteria.
Meibomian Gland Dysfunction (MGD) affects Tear Film (TF) stability, causing ocular irritation and dry eye. We conducted a prospective clinical study that included evaluating the TF Lipid Layer Thickness (LLT) in subjects with increasing severity of MGD. In an exploratory clinical trial (NCT01979887), TF LLT was measured with an ocular surface interferometer at two subject visits.
In recent years, the prevalence of myopia or eye illnesses in adolescents has remain ed high, with younger onset ages and increasing degrees of myopia. Adolescents' understanding of the reasons of myopia.
We report the case of a 52 -year-old male patient with no particular previous history, presenting to the emergency ophthalmology with Unilateral conjunctival mass in the right eyes that had progressively increased over the last two months.
The motor potentiation effect of grasping behaviors, namely the fact that the mere perception of agrasping object facilitates compatible motor response. According to the simulationnist account [1], ata conceptual level, there would be an involvement of motor processes, which will produce motor simulation.
Background: Coronavirus disease 19 (COVID-19) has been associated ophthalmic sequelae following recovery. Purpose: This study explores the possible role of the severe acute respiratory syndrome corona virus (SARS-CoV-2) in ophthalmic manifestations by analyzing the ocular samples.
A 35-year-old male presented with complaints of diminu tion of vision and floaters in OS for 2 months. Best corrected visual acuity was 20/20 and 20/80 in OD and OS respectively.
ChatGPT, an open-source Artificial Intelligence (AI) chatbot, utilizes deep learning to generate human-like textual dialogues. Its potential applications within the scientific community are extensive, yet its effectiveness in providing innovative ideas on various topics remains unexplored.
To evaluate the overall performance of various Artificial Intelligence (AI) models in ophthalmology for the diagnosis of various ophthalmic diseases despite of variations in methodology, platforms built, and workflows. AI technologies can revolutionize ophthalmology and vision sciences through automating image analysis.
We report the case of a 4-year-old, only child in his family, with no personal or family history. He consulted for a leukocoria of the left eye never explored before. Ophthalmologic examination of the left eye revealed visual acuity reduced to light perception.
This is a wide field fundus photograph of the right eye of an 83-year-old patient with wet AMD. The image shows extensive sub retinal haemorrhage involving the macula and extending superiorly and inferiorly with serous retinal detachment inferiorly as a complication of wet AMD. Best corrected visual acuity dropped from 6/9 to HM. The patient underwent Intravitreal injection of Tissue plasminogen activator (tPA), Anti-VEGF and gas to displace the blood from the macula.
To describe a relatively simple technique for fundus photography in humans using a smartphone and an indirect ophthalmoscopy lens. Fundus images were captured using smartphones (iPhone and android) and a 2.2 mm, 20 D, or 28D Pan retinal® lens. Using the phone’s light source, this system functions as an indirect ophthalmoscope that creates a digital image of the fundus.
Retinal damage can lead to severe and permanent visual loss. Mesenchymal stem cell and their secretome containing stem cell-derived factors and have been shown to have proliferative and anti-inflammatory properties. Therefore, the aim of this study was to assay the conditioned medium derived from the stem cells from apical papilla (SCAP) on retinal toxicity induced by H2O2 in rats.
A 6-year old boy was referred to the oculoplastic team for repair of a left upper lid laceration involving the superior canaliculus. He had presented to the eye casualty following a fall at home onto the plastic tip of a child size umbrella, which was un-witnessed. On examination, he was alert and oriented with a GCS of 15. There was a 1cm partial thickness oblique laceration of the left upper eyelid extending into the medial canthus, transecting the superior canaliculus.
Purpose: To assess the prevalence of ocular metastasis in pancreatic cancer (PC) as little is known in the literature.
Methods: Prospective cross-sectional study of consecutive patients with PC at the time of initial diagnosis in one medical center. Complete eye exam was performed by a single operator. A literature review was done to collect cases of metastatic eye disease in PC.
Ultrasound being a portable imaging device that is capable of making fast regional estimates of body composition, is an attractive assessment tool in instances when other methods are limited (risks of contrast in MRI and or radiation in CT scan). Furthermore, much of the research suggests that it is reliable, reproducible, not only an accurate means of diagnosing Thyroid Associated Orbitopathy (TAO) pathology and predicting its clinical course, but as a way to follow the course of the disease and the response to treatment as well...
Peripheral facial paralysis is a diagnostic challenge. Acute facial palsies are mostly “idiopathic” (Bell’s palsy) but it is a diagnosis of exclusion, and therefore cases of acute, acquired, isolated peripheral facial paralysis should be investigated thoroughly. Comprehensive efforts should be made to diagnose the cause, because some percentages of the patients referred with a diagnosis of Bell’s palsy were found to have a treatable, progressive, or life-threatening lesion.
Ultrasonography contains a wide selection of clinical indications. For instance, when examining a patient with ocular discomfort or pain, clinicians will use ultrasound to ensure a diagnosis of inflammation, orbital myositis, or dacryoadenitis. Imaging is often used to identify retrobulbar tissue, as well as the extraocular muscles, in patients with symptoms and suspected soft tissue enlargement secondary to Graves’ disease.
Age-related Macular Degeneration (AMD) is regarded as one of the main causes of irreversible vision loss in the elder. The increasing number of AMD patients is expected to reach 288 million by 2040. Detecting methods based on fundus images have become the main diagnostic approach for AMD. Therefore, this paper makes a systematic review analysis of AMD diagnosis based on fundus images. Methodologies of bibliography and text mining are included...
Purpose: To determine the effect of atropine on axial length elongation by prospectively examining axial lengths and parameters of refraction in atropine treated and untreated eyes of myopic children.
Design: Randomized prospective clinical trial.
Methods: Four hundred and ninety-two myopic children participated in this study. (Mean age 10.1 years, ranging 5 and 16 years) Initial examination for both treated and control groups included cycloplegic refraction (initial refraction between -0.50 and -3.50D), tonometry, keratometry and axial length measurement by A-scan ultrasonography...
Aim: Evaluating the efficacy of fresh Human Amniotic Membrane (HAM) for various ocular surface reconstructions.
Materials and methods: 54 eyes of 50 patients having ocular surface disorders were evaluated. Out of which 31 patients were male and 19 were females. Indications for AMT included pterygium (18 eyes), bullous keratopathy (4 eyes), climatic droplet keratopathy (3 eyes), Steven Johnson syndrome (14 eyes), chemical burn (3 eyes), corneal ulcer (7 eyes), band keratopathy (2 eyes) and shield ulcers (2 eyes). Fresh amniotic membrane was used in all the cases...
A 65-year-old male came to our OPD for routine eye checkup. He had no ocular complaints. His history was uneventful. On examination, his best-corrected visual aquity was 6/6 in both the eye. Ocular movements, pupillary reaction, intraocular pressure and Colour vision were normal. Examination of the fundus of the left eye was within normal limits with a cup disc ratio of 0.3 while the right optic disc had a cup disc ratio of 0.7...
Purpose: To report a case of ocular chemical burn caused by intentional topical self-administration of bitter melon (Momordica charantia) juice to treat presbyopia symptoms.
Methods: This is a case report and brief review of related literature
Results: A 45-year-old male presented with irritation, pain and discharge in the right eye after an intentional instillation of bitter melon juice in order to treat his new-onset of presbyopia symptoms. Best corrected visual acuity (BCVA) was 20/100 OD...
Clinical relevance: It is significant to determine main endothelial cell loss peak decades in order to decide surgical intervention time and be prepared for vital precautions in patients requiring ocular surgery.
Background: Although, endothelial cell loss during natural course of aging is an obvious clinical manifestation, remarkably in some ethnicities such as Turkish population, younger decades tend to have one of the main loss peaks...
This photograps belongs to a 75-year-old diabetic woman who presented to our clinic with bilateral progressive decreasing vision from a few years ago. She had a best-corrected visual acuity of count finger at 2 ms in her right eye and 20/200 in the left one by the Snellen chart. On the slit lamp examination, multiple clusters of poly chromatic and highly reflective needle-like crystals were seen within the cortex of the lenses of both eyes. In this case, the patient also had a Moderate to severe non-proliferative diabetic retinopathy and macular ischemia in her both eyes, which was the main cause of reduction of her vision.
Purpose: To characterize long-term Intraocular Pressure (IOP) and IOP-lowering medication reductions through 3 years following Excisional Goniotomy (EG) using the Kahook Dual Blade (New World Medical) combined with phacoemulsification in Bolivia.
Methods: This was a single-surgeon, retrospective analysis. Preoperative and postoperative IOP and medication use data were collected through 3 years of follow-up. Changes from baseline were analyzed using paired t-tests.
Background: To report three cases of Intrapapillary Hemorrhage with Adjacent Peripapillary Subretinal Hemorrhage (IHAPSH) in Chinese adolescents, and to review the published literature on IHAPSH.
Case presentation: Three patients were diagnosed with IHAPSH in a tertiary ophthalmic centre in Hong Kong between 2007 and 2019. All patients were young Chinese with moderate to severe myopia, and crowded/tilted discs, presenting with unilateral optic disc hemorrhage...
The ongoing COVID-19 pandemic plaguing countries worldwide has created an unprecedented change for the global economy, especially healthcare institutions at the forefront. Acceleration of the online-offline integration is the need of the hour. Massive expansion of home-based care likely will be supplemented with Artificial Intelligence (AI). One particular sector that has the greatest potential to benefit from tele-health services is the rural sector across all countries...
Objective: To formulate a protocol for safe and effective management of an ophthalmologic practice in a hospital or a clinic during the Covid - 19 pandemic.
Methods and analysis: Literature was reviewed regarding Covid-19 pandemic and ophthalmology. The following key words were used. Covid-19, telemedicine, challenges, management strategy.
Background: Various treatments modalities have been advocated to treat patients with glaucoma or OHT. Selective Laser Trabeculoplasty (SLT) has been highlighted recently for treatment of glaucoma patients.
Objectives: To analyse the reduction of IOP with SLT treatment.
Design: A retrospective study on 24 eyes treated with SLT treatment.
Introduction: Actions taken to carry out sustainable practice in ophthalmology during the COVID-19 pandemic have put the training process at an impasse. There is an enormous reduction in surgical volume and patient care by residents.
In this article the authors discuss the primary challenges faced by ophthalmology residents during the pandemic and propose potential solutions.
Participants: POAG or OHT patients in one or both eyes who were aged ≥ 18 years, able to provide informed consent, visual acuity of at least 6/36 in the study eye with suboptimal IOP control despite on antiglaucoma medications. Patients were excluded if they had congenital, early childhood or secondary glaucoma or ocular comorbidities, if they had any previous ocular surgery except phacoemulsification. Patients in the SLT group should not have previous SLT treatment before.
Our previous proteomic and biochemical studies suggest that the respiratory chain complexes I to V are expressed in the rod Outer Segment (OS), an organelle devoid of mitochondria, specialized for visual transduction. The expression of the cited proteins was demonstrated with several imaging techniques, even though co-localization only proved significant on retinal sections.
Introduction: Mowat-Wilson syndrome is a rare genetic condition resulting in multiple congenital anomalies including facial dysmorphism, structural anomalies of the internal organs, functional disorders and, although less commonly, ocular abnormalities.
Aim: To present a child with Mowat-Wilson Syndrome and eye abnormalities.
Background: The aim of the study was to evaluate the visual organ in children with severe hypoxic-ischemic encephalopathy treated with controlled hypothermia.
Methods: Controlled hypothermia was performed in the Neonatal Intensive Care Unit in Zabrze using the CritiCool & Cure Wrap System. Children were qualified and examined by neonatologists. All children were treated with whole-body hypothermia for 72 hours with a target temperature of 33 to 34°C in analgosedation with through biophysical monitoring.
Purpose: Report a case of Valsalva retinopathy that occurred during sport by analysing its clinical and therapeutic specificities.
Methodology: This is the report of a clinical case received in consultation on Monday 21st December 2020 at the ophthalmological investigation department of the IOTA-Teaching Hospital.
Here Hypermetropia in a 4 year old with zonular cataract (Figure 1a) is demonstrated with red reflex with indirect ophthalmoscopy as a bright area is seen in inferior part of the eye (Figure 1b) [1,2,3]. It is hard to pick up the same sign using red reflex with direct ophthalmoscope (Figure 1c) due to lesser distance between illumination and visualization axes in direct ophthalmoscope (as compared to indirect) allowing formation of better crescent that too just only through a peripheral rim...
Aim: To investigate the relationship between OSDI (Ocular Surface Disease Index), the Schirmer test, and tear Break Up Time (BUT) measurements in patients with pterygium and compare this according to pterygium grades. Methods: The BUT measurements and the Schirmer tests were evaluated in patients with pterygium, and OSDI questionnaires were applied. OSDI scores were calculated, and the patients were grouped according to their OSDI scores.
A 48 years old female presented to us with defective vision in both the eyes since 1 year. Her BCVA in RE was 6/18 and in LE 6/9. Both eyes anterior segment examination was within normal limits and posterior segment showed glistening, yellow-white intraretinal crystals in the posterior pole, atrophy of the retinal pigment epithelium & choroidal sclerosis.
Spherical aberrations are known to increase after LASIK surgery. This can cause problems with the vision at night when the pupil size increases to adjust for the darkness. The purpose of this paper is to show through photographs how spherical aberrations affect image quality.
Background/aims: Serious eye diseases caused from exposure to solar radiation continue to be a global public health hazard. Within the electromagnetic spectrum, the ultraviolet (UV) band and some of visible light band (high energy visible (HEV) light) pose the greatest health hazard to the human eye from solar radiation exposure. Wearing appropriate sunglasses is the most practical and cost-effective way of protecting the human eye from harmful solar radiation...
Objective: To analyze the related factors of ocular trauma in ophthalmic inpatients and provide epidemiological data on local ocular trauma. Methods: 1137 cases of 1610 eyes with ocular trauma admitted to our hospital from January 2014 to December 2018 were selected for statistical analysis of general conditions, causes of injury, prognosis and complications.
Nitric Oxide (NO) is a well known endogenous gasotransmitter with profound effects on mammalian physiology and also possesses major therapeutic implications. Despite the known toxicity of this molecule when present above the optimal concentration, plays key signaling and regulatory role in human life processes. From the literature survey it is evident that NO bears potential role almost in every system of human body. Among these systems nervous system has also been found linked with this molecule.
The human eye, composed of specialized tissues, has unique functions to admit or receive certain wavelengths of electromagnetic radiation. In order to integrate information from the entire visual field, visible light is collected and focused by the spherical lens onto retinal neurons. Excessive light exposure, however, not only mediates photoreceptor activation but also induces photodamage effects.
A 71 year old man presented with a history of cataract surgery in both eyes and gradual diminution of vision post surgery in right eye (RE) since 3 years. On examination RE showed corneal decompensation with seclusio pupillae with a small pupil and a posterior chamber intraocular lens (PCIOL). He was diagnosed with pseudophakic bullous keratopathy (PBK). He underwent DSAEK (Descemet's stripping automated endothelial keratoplasty ) with synechiolysis and pupilloplasty. Graft lenticule was well attached to the host tissue with a vertically oval pupil and subsequent improvement of vision.
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