IMPACT FACTOR: 1.3
Short Name: Ann Biotechnol
ISSN: 2637-4927
Publisher: MedDocs Publishers LLC
Development of DNA aptamers through ten rounds of selection and PCR amplification (SELEX) against recombinant adult Cs44 and Egg proteins of Clonorchis sinensis liver flukes is described along with the top three aptamer DNA sequences for each target derived from next generation sequencing. ..
Recombinant DNA technology is a crucial method that involves separating and inserting a gene of interest into a specific vector. One important application of this technology is in combating Hepatitis B, a widespread infectious disease in humans, by developing effective vaccines and treatments. ..
Nature needs to shake off the dust built due to its exploitation by humankind. One such heavy blow was probably the current COVID-19 pandemic. The COVID-19 pandemic has enabled habitat restoration of various wildlife and natural resources, along side the economic challenges it has imposed with increased poaching in certain countries ..
Interpersonal relationship problems are key to Opposi tional Defiant Disorder (ODD). The study aimed to examine the types of interpersonal relationship problems, as pre sented in the Interpersonal Circumplex Model (IPC), with the ODD dimensions (oppositional, negative affect, and an tagonistic behavior) proposed by Burke et al. (2010).
The majority of Remnant Lipoproteins (RLP) in the postprandial plasma have been believed to be chylomicron (CM) remnants (exogenous remnants; RLP-apoB48) derived from the intestine, not VLDL remnants (endogenous remnants; RLP-apoB100) derived from the liver ..
The peel of orange and lemon fruits is considered as a waste. It is used as a source of essential oils that can be applicable for food flavoring agent, pharmaceuticals, cosmetics, and soap and detergent factories. In this work, essential oils were extracted from lemon (1.56%) and orange (3.55%) peels by hydro distillation. The physiochemical properties of oils were recorded...
In-depth analysis and thorough understanding of N-glycosylation is critical for therapeutic proteins. For IgG or IgG-like molecules, the conserved N-glycosylation at Asn-297 has critical safety and efficacy implications and therefore is under close scrutiny. Any additional N-glycosylation that increases complexity and heterogeneity of the molecule, should be avoided at the early stage of drug discovery. However, unexpected glycosylation at atypical sites brings unforeseen challenges for antibody drug development process...
The aim of this review is to show the distance between the technical side of OCT and the understanding and needs of the laryngologists. In updated scientific research on OCT in laryngology, especially of the vocal folds, there are some obstacles of the techniques before the clinicians can use optical coherence tomography routinely.
With skin cancer incidence rate steadily increasing each year, melanoma continues to pose a significant public health problem globally. It is well-known that early detection and prevention of melanoma remains the most important intervention for reducing morbidity and mortality, therefore it is imperative to promote innovation that will advance our ability to diagnose melanoma early...
Present day agriculture has disturbed the age-vintage stability of host-pathogen system resulting diseases arise at regular interval leading to significant loss to the agricultural production, that is predicted to be 10-25% or much less in the course of everyday years however might also additionally enlarge as much as 100 % in the course of epidemic. Broadly, there are breeding tactics followed for disease resistance, which incorporates molecular and molecular one...
Polycystic Ovary Syndrome (PCOS) accounts for a major form of dysovulatory infertility, often observed in ~15% women belonging to reproductive age. Being the etiology undecipherable and the management requiring a diversified approach, the call for a suitable animal model is warranted that will be able to mimic both reproductive as well as metabolic facets of the syndrome...
Background: Since the COVID-19 a pandemic disease, so far there are no drugs or other treatment practices currently approved by the U.S. Food and Drug Administration (FDA) to treat COVID-19 patients. Current scenario is only clinical management includes infection prevention and control measures and supportive care, including oxygen supplementation and mechanical ventilatory support when indicated...
Background: Prenatal diagnosis of Restrictive Dermopathy (RD) in routine ultrasonography is particularly challenging since most fetal ultrasonography RD findings are non-specific and appear during late pregnancy.
Background: Milk consumption and demand has increased drastically over the past years in response to expanding human population in Uganda and world at large. Despite this, many residents of Kampala city obtain milk from shops supplied by milk vendors, who in turn, collect it directly from farms. The microbial load of this unpasteurized milk is not known, yet it could expose the population to milk-borne diseases..
Monoclonal antibodies (mAbs) were raised against 43 kDa glycoprotein (gp43) of Paracoccidioides brasiliensis. One mAb anti-gp43 and gp43 were used in a double-antibody sandwich ELISA to detect antibodies in sera from patients with Paracoccidioidomycosis. This ELISA diagnosis showed 91.18% sensibility and 100.0% specificity against sera of patients with histoplasmosis, aspergillosis or chromomycosis.
Background: Highly Active Antiretroviral Therapy (HAART) consisting of at least three active drugs against HIV infection has improved HIV/AIDS management since their inception. However, alterations of lipid metabolism due to HAART can result into secondary diabetic and hypertensive renal damage. This study was carried out to assess the effect of antiretroviral drugs on the renal function of HIV seropositive patients by determining the serum levels of Creatinine, Urea and Electrolytes (Na, K, and Cl) of the patients on treatment.
Researches on the factors that inhibit senescence are attractive in health industries. Artemia extract uses in cosmetic and sunlight protecting products. The aim of this work was to study the effects of Artemia extract on the cell proliferation, senescence and collagen synthesis by human fibroblasts in normal and aging induced conditions.
Uterus Leiomyosarcoma (uLMS), unfortunately, is a disease with a poor prognosis. In the report of the Ministry of Health, Labor and Welfare, the 50% survival time (mOS) summarized from Stage I to Stage IV was 31months. Preoperative diagnosis of uLMS is very difficult. Although it is diagnosed as "uterine fibroids", it is not uncommon in cases where the uterine leiomyosarcoma is definitely diagnosed again after surgical hysterectomy or removal of myoma.
Nowadays most of the biotechnological processes can be performed on benchtop platforms without the need for an expensive, space-consuming equipment. In addition, the sensitivity and specificity of the conventional assays using biotechnological processes can be improved with the recent advancements in materials science and modern technology.
Recent years have witnessed significant advancement in 'self-healing' technologies. This is unlike a decade back, when 'self-healing' materials which are capable of restoring functionalities such as electrical conductivity or even optical (e.g., display) property after mechanical damage were practically non-existent. This editorial provides a quick introduction on reported 'self-healing' technologies,...
Honey is a potent natural antibacterial remedy used for the treatment of chronic wounds. In this study, Honey incorporated Acellular Dermal Matrix (H-AGDM) was fabricated for accelerating the wound healing process. The physiochemical and morphological characterization of the fabricated matrix was performed by FTIR, FESEM, in vitro degradation study, and antibacterial activity.
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Authors
Archna Dhasmana1*; Lubhan Singh2 ; Partha Roy3 ; Narayan Chandra Mishra1
1Department of Polymer & Process Engineering, Indian Institute of Technology Roorkee
2Department of Pharmacology, RIVET, Greater Noida
3Department of Biotechnology, Indian Institute of Technology Roorkee
Received: Jun 26, 2018
Accepted: Aug 15, 2018
Published Online: Aug 22, 2018
Authors
KOH Leng-Duei
Institute of Materials Research and Engineering, A*STAR, 2 Fusionopolis Way, Innovis, 138634, Singapore
Received: May 30, 2018
Accepted: Aug 27, 2018
Published Online: Aug 30, 2018
Authors
Shilpa Sivashankar1*; Prasad Salunke2
1Assistant professor, Department of Biotechnology, Acharya Institute of Technology, Bangalore, India
2Assistant Professor, Department of Mechanical Engineering, Acharya Institute of Technology, Bangalore, India
Received: May 03, 2018
Accepted: Sep 24, 2018
Published Online: Sep 27, 2018
Authors
Takuma Hayashi1,9,*; Tomoyuki Ichimura2 ; Mari Kasai2 ; Kenji Sano3 ; Susumu Tonegawa4 ; Yae Kanai5,10; Dorit Zharhary6,9; Hiroyuki Aburatani7 ; Nobuo Yaegashi8 ; Ikuo Konishi1
1National Hospital Organization Kyoto Medical Center, Japan
2Department of Obstetrics and Gynecology, Osaka City University, Japan
3Pathology Division, Iida City Hospital, Japan
4 Picower Institute, Massachusetts Institute of Technology, USA
4Picower Institute, Massachusetts Institute of Technology, USA
5Pathology Division, Keio University School of Medicine, Japan
6SIGMA-Aldrich Israel, Israel
7Research Center for Advanced Science and Technology, The University of Tokyo, Japan
8Department of Obstetrics and Gynecology, Tohoku University, Graduate School of Medicine, Japan
9SIGMA-Aldrich Collaboration Lab and Promoting Business using Advanced Technology, Japan
10The International Human Epigenom Consortium (IHEC) and CREST, Japan
Received: Aug 22, 2018
Accepted: Sep 25, 2018
Published Online: Sep 28, 2018
Authors
Neda Vaseli-Hagh1 ; Abdolkhaleg Deezagi*1 ; Mahvash Khodabandeh Shahraki2
1Department of molecular medicine & Biochemistry, National Institute of Genetic Engineering and Biotechnology, Tehran-Iran.
2Department of Technology & Environment, National Institute of Genetic Engineering and Biotechnology, Tehran-Iran
Received: Aug 29, 2018
Accepted: Oct 02, 2018
Published Online: Oct 05, 2018
Authors
Zelalem Zayse Zeleke
Wachemo University, Durame campus, Department of chemistry, Ethiopia.
Received: May 19, 2022
Accepted: Jun 14, 2022
Published Online: Jun, 16, 2022
Authors
Jing Jiao1; Liming Huang1; Xiaohui Xu1; Yuying Liu2; Mingyan Hu1; Weifeng Chen1; Lei Li1; Hui Xu1; Xugang He2; Nannan Li2; Aihua Chen1; Chenxi Shen2; Lei Wang2; Xun Liu3; Lianshan Zhang4; Chenxiang Tang1*
1Shanghai MabGen Biotech Ltd, China.
2Beijing Tuojie Biotech Co Ltd, China
3Shanghai Hengrui Pharmaceuticals Co Ltd, China
4Jiangsu Hengrui Pharmaceuticals Co Ltd, China.
Received: Apr 12, 2022
Accepted: May 07, 2022
Published Online: May, 09, 2022
Authors
Mette Pedersen1*; Christian Larsen2
1ENT-specialist, Medical Centre, Østergade 18, 1100, Denmark.
2 Stud. Can (it), Copenhagen Business School, Solbjerg plads 3, 2000, Denmark.
Received: Feb 10, 2022
Accepted: Feb 28, 2022
Published Online: Mar 04, 2022
Authors
Joanna Ludzik1,2*; Claudia Lee2,3; Alexander Witkowski2; Jonathon Hetts2; Sancy Leachman2
1Department of Telemedicine and Bioinformatics, Jagiellonian University Medical College, Krakow, Poland.
2 Department of Dermatology, Oregon Health and Sciences University, Portland, Oregon, USA.
3 School of Medicine, University of California Riverside, Riverside, California, USA.
Received: Jan 22, 2022
Accepted: Feb 15, 2022
Published Online: Feb 18, 2022
