Down syndrome and incidental pediatric basal ganglia calcifications at autopsy

Richard A Prayson

    Basal ganglia calcifications in the pediatric population are an unusual finding and in radiologic studies, have been noted in between 1-2% of patients in that age group. The causes for calcification are myriad but most commonly include tumors, congenital infections and tuberous sclerosis. The current report describes a case of a 17-year-old female with Down syndrome (trisomy 21) who presented with agitation, dry cough, decreased appetite, and fever. She experienced a 3 minute apneic episode followed by cardiopulmonary resuscitation...

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