IMPACT FACTOR: 1.2
Short Name: Neurol Neurol Sci Open Access
ISSN: 2641-0362
Publisher: MedDocs Publishers LLC
The relevance of fluid shifts related to the impaired competence of the blood brain barrier in the absence of traumatic brain injury may be under-recognized and the clinical impact of shifts of fluids in the brain in the context of an acute systemic illness may pose a challenge to neurologists, intensivists and radiologists.
The Covid-19 pandemic has left very effective traces in every area in the world, and the health areas have been the most affected by this situation. One of these affected health areas is dentistry. In this study, the efficiency of the neuroanatomy course, which is difficult to understand even in face-to-face education, in the distance education process and alternative ways were evaluated through student opinions.
We identified a subset of 137 patients from the Greater Cincinnati/Northern Kentucky area (GCNK Region; Hamilton and Clermont counties in Ohio and Boone, Campbell, and Kenton counties in Kentucky) who had a diagnosis of cancer before a stroke. Then, further analysis was performed on the 98 patients within this population who had an ischemic stroke or TIA.
Aims: In this cross-sectional study from Botswana (upper middle-income country), the objective was to investigate awareness and knowledge of cardiovascular diseases as stroke risk factors, acute stroke treatment and secondary prevention among medical doctors.
To investigate the localizing ability and surgical outcome using 3D-EEG Source Imaging (3D-ESI) Moving Dipole (MD) methodology in children with Tuberous Sclerosis Complex (TSC). We retrospectively studied a cohort of pediatric patients with TSC and multiple tubers undergoing excisional surgery for drug resistant epilepsy.
Purpose: The study exposes the challenging situation of students with ASD (Autism Spectrum Disorder) in the COVID-19 pandemic in Bangladesh and manageable strategies to meet the educational, physical and psychological needs of students with ASD.
Methodology: This qualitative research was conducted in two phases: information collection from parents of students with autism and looking for solutions from professionals. The snowball sample technique was selected for both phases due to the social distance rules.
Neuroinflammation is a key factor leading to the occurrence of neurodegenerative diseases. Human Umbilical Cord Mesenchymal Stem Cells (hUC-MSCs) exert anti-inflammatory functions. However, the mechanism of the effect of hUC-MSCs therapy on the intestinal flora of neuroinflammatory models is still unclear. The purpose of this study is to explore the regulatory effect of hUC-MSCs on the intestinal flora of the LPS-induced neuroinflammation models...
Object: Still, the question about the specific treatment of patients with SNTs of the cervical spine segment with paravertebral growth is insufficiently studied. This requires close attention and needs further improvement, which proves the relevance of the chosen topic and research area.
Solving the problem of improvement of treatment of SNSTs of cervical spine consists of evaluating the results of surgical treatment, and advanced surgical approaches used to remove these tumors.
Amyotrophic Lateral Sclerosis (ALS) is a progressive motor system disease involving upper motor neurons (corticospinal tract) and lower motor neurons (anterior horn cells). Asymmetrical distal weakness of one limb or bulbar weakness is the typical presentation. Subacute respiratory failure rarely occurs before the diagnosis is established. We present a case of respiratory failure from ALS that appeared after lumbar surgery following a prodrome of “benign” fasciculation’s.
Thoracic myelopathy is quite rare and can present with a false localizing sensory level. Knowledge of its clinical features is essential to a timely diagnosis and treatment. Magnetic Resonance imaging of the thoracic spine is the test of choice to confirm the diagnosis. Lack of imaging of the neural elements by computed tomography masks spinal cord injury. We present four cases highlighting diagnostic missteps and clinical features to guide clinical management before and after surgical decompression.
Objectives: In this cross-sectional study from Botswana, we investigated awareness and knowledge of ischemic stroke symptoms among healthcare professionals based on healthcare levels.
Method: Questionnaires including five common stroke symptoms and three detractors were administered to a representative selection of doctors, nurses, and paramedics working in both government and private primary and secondary healthcare facilities...
Remdesivir, an inhibitor of viral RNA polymerase, was initially developed as a potential treatment for hepatitis C and subsequently studied in Ebola, Severe Acute Respiratory Syndrome (SARS), and Middle East Respiratory Syndrome (MERS) outbreaks. Now, the Coronavirus Disease 2019 (COVID-19) pandemic has increased the global utilization of remdesivir as an experimental therapy for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)...
Physical trauma to the Central Nervous System (CNS) activates different responses at the cellular level. Microglia as one of the first mediators of the inherent immune response in CNS plays a vital role in neuronal tissue damage and consequent neuroinflammation. Various characteristic features of microglia, such as gene expression, morphology, and functional activity can be affected by different pathological conditions. Once microglia chronically activated following a Traumatic Brain Injury (TBI), the release of pro-inflammatory mediators and reactive oxygen species is increased, which may lead to further neural tissue damage.
Von Hippel-Lindau disease is an inherited, autosomal dominant tumor predisposition syndrome which leads to susceptibility for developing hemangioblastomas of the central nervous system and retina, as well as other tumor types. No approved systemic therapies exist for this disease. Here, we present a patient diagnosed with Von Hippel-Lindau disease, with central nervous system and retinal hemangioblastomas, treated with propranolol and subsequently with Lanreotide.
Aim: To evaluate low dose gabapentin in treatment of disruptive behavioral symptoms in patients with moderate- severe dementia with Lewy bodies.
Findings: Improvement in symptoms seen by clinician and caregivers supported by changes on respective scales.
Message: Preliminary positive evidence suggesting that low dose gabapentin can be used for treatment of patients with dementia with Lewy bodies.
Objective: C-reactive protein (CRP) has been associated with Ischemic Stroke (IS) risk and short-term outcome. We evaluated the association between the CRP rs1130864 variant (+1444 C>T) with susceptibility and short-term outcome of IS and levels of CRP.
Methods: We enrolled 168 IS patients and 166 controls. Baseline characteristics and blood samples were obtained up to 24 hours of hospital admission. The disability was evaluated using the Modified Rankin Scale (mRS) after three months and categorized as mild (mRS⟨3) and moderate/severe (mRS≥3)...
Thoracolumbar junction is the transition segment between the relatively stiff thoracic spine and the mobile lumbar spine. This region especially predisposes for injury due to absence of costovertebral structures that provide additional supporter for vertebral column, and uncompleted transition to the full lumbar lordosis; and it is considered biomechanically the weakest point in the spine.
Ki-67 proliferation index is widely used for differentiating between high and low-grade gliomas, but differentiating between the same grade IV appears to be more problematic, and the point about its prognostic value for GBM patients remains unclear. To reduce the possibility to find a marked histological heterogeneity, and may contain areas that could be diagnosed as lower grade.
We describe a rare case of a cerebellar ganglioglioma in a 31-year-old woman discovered incidentally during a CT scan of the parotid glands. CT and MRI features are not specific, with mixed cystic and solid components with calcifications. Although rare, our case demonstrates that cerebellar ganglioglioma must be considered in the differential diagnosis of infratentorial tumors in young adult patients...
Objectives: Examination findings of cervical disc disease and shoulder disorders are similar. Therefore, it is difficult to distinguish these pathologies only by physical examination...
The Congenital Myasthenic Syndromes (CMS) are a group of neuromuscular diseases caused by genetic defects of muscle endplate. Symptoms are present at birth but may go unrecognized until adolescence or adulthood when clinical manifestations are mild and progression is gradual. Autosomal recessive inheritance account for all genetic forms except for slow channel syndrome having an autosomal dominant mode of inheritance...
The patient was a 37-year-old woman with a past history of hypertension, convulsion, palpitation and depression who experienced tonic convulsion at her home. She was transported to our hospital. After the initial arrival, she had a 2nd convulsive episode in the emergency room. A neurologist checked her. As her vital signs were stable and she was free of neurological symptoms, the neurologist decided to discharge her to home...
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