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Molecular Insights of Exonal Polymorphism in Cancer Risk

Rashmi Kumari; Siya Ram; M M A Rizvi; Madhu Rani*

   Single nucleotide polymorphisms are a sort of genetic variations, have been identified in numerous genes that linked to various cancer types. SNPs in exon regions of hub cellular of genes that influence gene expression


Metastatic Sacral Chordoma - A Case Report Unveiling the Achievements and Progress in Recent Management Strategies

Ezhil Sindhanai M Parvath*; Rajesh Balakrishnan*; Selvamani Backianathan; Patricia Sebastian; Raju Titus Chacko; Rima S

    Chordomas are rare tumors that grow slowly, tend to recur locally and seldom metastasize. They originate from residual primitive notochordal tissues along the axial skeleton and are typically found in the sacrococcygeal region (50%), clivus (35%), and vertebral bodies (15%). The median reported survival is 6.29 years with a 10-year survival rate of 39.9%.


Rectal Adenocarcinoma in Brca 2 Carrier Case Report

Juan Carlos Redondo-González*; Teresa Martín Gómez; Eva María Sánchez Tapia; Luis Posado Domínguez; Pablo Díaz Sánchez; Daniel Morchón Araujo; Edel del Barco Morillo; Emilio Fonseca Sánchez

    The relationship of mutations in the BRCA 2 gene has been established with some types of tumors, especially breast, ovarian, prostate, or pancreatic cancer. However, the relationship between the development of colorectal tumors and type of genetic alteration is not entirely clear.


Organ Preservation in Advanced Laryngeal Cancer Using Radical Radiotherapy: A Case Series

Bhuvana J*; Vinay Shivhare; Satyajeet Rath; Ankita Parikh; Suryanarayan U

    Advanced laryngeal cancers are conventionally treated by total laryngectomy but surgical intervention has a profound impact on quality of life. Role of radiotherapy in laryngeal cancer with extensive extra laryngeal spread is limited. Therefore, we did a study of the case series to investigate the survival outcomes and laryngeal preservation after radical radiotherapy in advanced laryngeal carcinomas with extensive extra laryngeal spread.


Current Developments in Laparoscopic Surgical Technology: A Summary of Progress

Hassan Awad Saad*; Azza Baz; Mohamed Elsayed Eraky; Ahmed Kamal El-Taher; Mohamed Riad; Mohamed Ibrahim Farid; Khaled Sharaf

    With its less invasive technique and quicker recovery periods, laparoscopic surgery—also referred to as minimally invasive surgery or keyhole surgery—has completely changed the surgical sector. Significant developments in laparoscopic methods, tools, and technology in recent years have enhanced patient outcomes and broadened the scope of surgical applications.


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