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Adult Hirschsprung's Disease

Wondemagegn Gizew; Murtii Teressa*; Kibrom Legesse; Eyerusalem Fissahatsion; Fekade Yerakly; Mishame Damtew

    Although the primary pathology of Hirschsprung's disease is a congenital gut motor neuron development disorder causing functional intestinal obstruction, which is diagnosed in over 94% of cases with clinical evidence and histologic examination before children reach the age of five, the term "adult Hirschsprung's disease" is conventionally used as a clinical trend when the disease is diagnosed in an adult who is older than ten years.


Angiomyxolipoma of the Forehead: A Case Report and Review of the Literature

Christine Vella*; Clifford Caruana; Denys Skoryi; Daniel Chircop

    Angiomyxolipoma is a rare, benign soft tissue tumor characterised by the presence of mature adipose tissue, myxoid stroma, and a prominent vascular component. This case report details the clinical presentation, histopathological features, treatment, and follow-up of a 59-year-old male patient diagnosed with angiomyxolipoma of the forehead.


A Case of Appendiceal Neurofibroma Presenting As Appendicitis

Tasneem Farag; Reem Ali*; Jane Kim; Jessica Wassef

    Intra-abdominal neurofibromatosis is an exceedingly rare diagnosis constituting a challenge for clinicians in diagnosis and management. With only a few cases reported worldwide, there is no consensus on management protocol. Because appendiceal neurofibromas are benign, surgical excision is the main therapeutic option, and the prognosis is usually good.


A Case Report of Rectosigmoid Prolapse Secondary to Pedunculated Adenomatous Polyp

Natnael Gebeyehu; Muluken Simachew; Solomon Bekele; Aisha Jibril Suleiman; Solyana Bereded; Biruk Tesfahun Mengistie*; Chernet Tesfahun Mengistie

    Rectal prolapse is defined as entire thickness rectum protrusion past the anal sphincter. The prolapsed section of the rectum can become cancerous in rare cases. Although the exact incidence of rectal prolapse is unknown, it is a relatively uncommon condition. We present a case of rectal prolapse accompanied by neoplastic transformation.


Primary Neuroendocrine Tumor of the Breast: A Rare Case Report

She's Magnolia Ycong; Hannah Lois R Kangleon-Tan; Kristoff Armand E Tan

    Primary neuroendocrine tumors of the breast are an uncommon and often overlooked subtype of breast carcinoma primarily affecting postmenopausal women. These rare tumors account for approximately 2-5% of all breast cancers and are classified as well-differentiated Neuroendocrine Tumors (NETs)


A Case of a 70year Old Operates with Severely Calcified Sinus of Valsalva Aneurysm: Did we Judge it Correctly in the First Place and Did we React Properly in a Rapidly Worsening Situation

Aysun Tulun*; Johannes M Albes

    Surgery for a severely calcified sinus of Valsalva aneurysm can be challenging. We present a patient in whom a simplified approach did not suffice so that implantation of a composite graft was required combined with individual grafts to the coronary ostia instead of direct re-insertion into the prosthesis because of the high calcification load.


Diagnosis of High Bifurcation of the Abdominal Aorta and Associated Aneurysmal Dilatation in Different Parts Detected by Multidetector Computed Tomography: A Case Report Study

Liaquat Khan; Ans Malek*

    The abdominal aorta is the main blood vessel in the abdominal cavity that transmits oxygenated blood from the thoracic cavity to the organs within the abdomen and to the lower limbs. Variations of the branches and bifurcation of the abdominal aorta with their relations with other abdominal and spinal structures are so important regarding abdominal and spinal surgery.


Acute Inferior Myocardial Infarction Caused By Spontaneous Coronary Artery Dissection: A Case Report

Shengsheng Xu; Yuqi Pang; Xiangyong Wang; Jianhua Xie; Kunhao Zhu; Jianxiong Liu*

    Spontaneous Coronary Artery Dissection (SCAD) is a disease caused by spontaneous tear of coronary artery intima or spontaneous bleeding in the vessel wall, which affects or blocks coronary artery blood flow. It is an important cause of non atherosclerotic acute coronary syndrome and acute myocardial infarction. In this case report the patient was treated with coronary angiography in the catheter room, temporary pacemaker implantation and intravascular ultrasound (IVUS).


Progress in Research Regarding Role of Circular RNA in Colorectal Cancer: A Review Article

Xie Yin*; Wu Chunyu

    Circular RNAs (Circ RNAs) are a group of endogenous non-coding RNAs (ncRNAs) which widespread in eukaryotic cells, and have been brought to the research hotspots recently. As a member of ncRNAs, Circ RNAs may play an important part in diseases by regulating target gene expressions, via epigenetic modifications. Colorectal Cancer (CRC) is a common malignant tumor worldwide, and its progress may be attributed to the dysfunctional expressions of target genes...


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