Archive

Subcutaneous Administration of Anticancer Agents: A Narrative Review

Marzieh Mogharrabi; Mostafa Kamandi; Abolghasem Allahyari; Amir Hossein Sahebkar; Hamed Baharara; Omid Arasteh*

    Intravenous (IV) administration is considered as the primary route of administration for many anticancer agents. However, there are some limitations such as the possibility of postinjection infections and catheter failure.


An Unusual Presentation of Sarcoidosis Mimicking Metastatic Peritoneal Carcinomatosis – A Case Report and Review of the Literature

Lauren Scanlon*; Gary L Goldberg; Jill Whyte

    Sarcoidosis is a multi-organ system autoimmune disorder characterized by the presence of non-caseating granuloma formation within one or more organ systems [1]. The majority of cases present with lung involvement, however 30-50% of cases have extra-pulmonary involvement at the time of clinical presentation [2].


Lung Cancer with Multiple Cutaneous Metastases – A Diagnostic Dilemma

Aprajita

    Cutaneous metastases of the different visceral malignancies (0.7-9%) and especially of the lung cancer are rare and worsen the prognosis (1-12%). We report the case of a 55 year old gentleman who presented with a right upper lung lesion diagnosed as poorly differentiated squamous cell carcinoma and was treated with concurrent chemo radiation therapy followed by adjuvant chemotherapy.


A Case of Large Lymph-Node Metastasis from Tongue Cancer with a Complete Response Maintained Even After Discontinuation of Cetuximab Plus Paclitaxel Combination Therapy

Kaname Sakuma*; Eizaburo Kobayashi; Shuji Toya; Akira Tanaka

    The combination therapy of the epidermal growth factor receptor inhibitor, cetuximab (Cmab), and paclitaxel (PTX) can be possibility effective for treatment of large cervical lymph-node metastasis. Here, we report a case of a patient with large cervical lymph-node metastasis treated with Cmab+PTX in whom complete response (CR) was maintained even after treatment discontinuation at the request of the patient. The patient was a 55-year-old female with a chief complaint of left-tongue pain...


Cystic Renal Cell Carcinoma vs Cystic Degeneration in Renal Cell Carcinoma: Major Disparity in Prognosis in a Seemingly Same Entity

Vikas Sankar K; Pradyumna K Sahoo*; Sunil K Agrawala; Sangram Keshari Panda; Sudam Sadangi; Prathamesh C; Tim Houghton T; Ramkishan Nag

    Cystic degeneration is common in Renal Cell Carcinoma (RCC) in about 15% of the cases [1]. This has to be differentiated from the cystic variant of RCC. This is difficult due to the expanding subtypes being described as the number of cases seen and being studied are increasing. A seemingly cystic degeneration in RCC can easily be a multilocular variant of cystic RCC with solid component of less than 25%. The prognosis of the patient varies according to the diagnosis and thus the aggressiveness of the treatment needs to be tailored. Here we present such a diagnostic dilemma...


Autoimmune Like Hepatitis Post Allogeneic Hematopoietic Stem Cell Transplant: A Case Report

Chung-ting J Kou*; Gilbert Ancira; Matthew Rendo; Devin Broadwater; Janelle Gyorffy; Bradley Beeler

    Hematopoietic stem cell transplant is the standard of care in the management of multiple hematological malig-nancies. Infections, graft-versus-host disease and primary disease relapse are known complications of hematopoietic stem cell transplant which contribute to morbidity and mor-tality. Immune mediated complications post hematopoietic stem cell transplant is an under recognized phenomena due to its heterogeneous presentation which can have clinical overlap with graft-versus-host disease.


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