Neoplasm metastasis is a multi-step and multi-level pathological feature causing 90% of cancer mortality due to a shortage of effective drugs and clinical therapeutics. To change this scenario, new drug targets and developments are required. Aberrant tumor sialylation as a putative drug target candidate has been evolving over the past half century.
Medicinal value of a plant depends to a large extent on phytochemicals present in it. The biochemical profile of mature and immature fruits of Drypetes roxburghii was assessed by making an estimation of some of primary and secondary metabolites present in it. Among the tested primary phytochemicals carbohydrates, starch, protein, lipids were present in sufficient amount.
The pyrazolic nucleus has a multitude of activities such as analgesic, antiarrhythmic, local anesthetic, antimicrobial, anticonvulsivant, anti-tumor, antidiabetic, antipyretic, antiviral, antimalarial, and so forth. The literature is extremely abundant in the study of pyrazoles, their synthesis and medicinal applications.
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