Hyaluronic acid has long been used as an infiltrative therapy for osteoarthritis. Besides its physical properties of shock absorption, one of its primary effects is to reverse the inhibition of proteoglycan synthesis and attenuate osteoarthritis's oxidative stress reaction cascade. However, clinical trials provide controversial results regarding its effectiveness. One possible explanation is its fast clearance rate due to reactive oxygen species...
The presence of joints in the human body is an important element for life. But with age, as well as under the influence of damaging factors (injuries, infection, metabolic disorders, etc.), pathological changes can develop in the joints that make it difficult to move in them. Currently, a common method of treating osteoarthrosis is endoprosthesis, which has been used since adolescence.
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