Artificial Intelligence and Enhanced Colonoscopic Imaging Surveillance for Inflammatory Bowel Disease: Beyond Random Biopsies

Edward C Oldfield IV, MD; Byung Soo Yoo, MD; Esteban J Figueroa, MD; David A Johnson, MD MACG FASGE MACP*

Inflammatory bowel disease confers an increased risk for colorectal cancer among individuals with long standing colonic disease. Current guidelines for optimal management of these patients recommend high quality surveillance colonoscopies every 1-2 years, performed during times of quiescent disease. In many instances, dysplastic changes can be difficult to visualize endoscopically in these patients. Accordingly, there has been increasing use of endoscopic advances to assist in the diagnosis and management of dysplasia...


Adjunctive Therapies for Inflammatory Bowel Disease: Beyond Prescriptions

Lindsey B Cundra, MD; Steve M D'Souza, MD; Byung S Yoo, MD; David A Johnson, MD MACG FASGE MACP*

Ulcerative Colitis (UC) and Crohn’s Disease (CD) comprise the two major subtypes of Inflammatory Bowel Disease (IBD). IBD is a chronic relapsing-remitting disease with an underlying etiology that remains imperfectly understood. Complementary, or integrative, medicines are emerging therapies for patients with IBD. They provide a useful adjunct to conventional therapies, further augmenting clinical outcomes through quality-of-life measures and symptom management...


Correlation Between Changes in the Gastrointestinal Microbiota with the Onset and Complications of Parkinson’s Disease: The Role of Inflammatory Cytokines in the Bidirectional Gut-Brain Axis

Pablo Cleber Sousa Lopes Sales*; Almir Vieira de Sousa Neto; Lahuan Araujo Costa; Mikhail de Morais Veras da Fonseca; Luan Kelves Miranda de Souza

Humans developed a symbiotic relationship with their gut microbiota, a complex microbial community made up of bacteria, archaea, protists, and viruses, including bacteriophages. The enteric nervous system (SNE) is a gateway to bidirectional communication between the brain and the intestine, mainly through the Vagus Nerve (VN). Therefore, environmental exposure plays a fundamental role in both the composition and functionality of the intestinal microbiome and can contribute to susceptibility to neurodegenerative disorders, such as Parkinson’s disease (PD)...


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