Targeting Alzheimer's Disease Through Pharmacoinformatics: New Challenges in Drug Design

David Ramírez*; Lily Arrue; Miguel Reyes-Parada

Neurodegenerative diseases associated with dementia are highly prevalent, and it is estimated that about 35 million people worldwide suffer some type of dementia, with Alzheimer’s Disease (AD) being the most frequent condition. Three hypotheses have been postulated in the pathophysiology of AD: cholinergic, amyloid and neurofibrillary tangles.


The Parents as "Prima Authors" Structures and Mechanisms of Parenting and its Effects on Child and Family Development

Anat Ben Salmon*; Ofer Erez

Karraker and Coleman (2006) [1], extensively discussed that in recent years, research has been invested in expanding an understanding of the many individual and environmental factors impacting parenting and the influences of the differences in parenting styles on child developmental consequences (Karraker and Coleman, 2006).


Exploring and Exploiting a Common Pathophysiology of Type 2 Diabetes and Alzheimer’s Disease

Syed Abdul Kader

In the aging population, Type 2 Diabetes Mellitus (T2DM) and Alzheimer’s Disease (AD) are two of the most prevalent diseases worldwide. It is evident from epidemiological studies that people with T2DM are at a higher risk of developing AD. On the other hand, in AD brains are less capable of glucose uptake from the surroundings resembling a condition of brain insulin resistance. Pathologically AD is characterized by extracellular plaques of Amyloid β (Aβ) and intracellular neurofibrillary tangles of hyperphosphorylated tau...


The Use of Antipsychotic Drugs in Patients with Alzheimer’s Disease

Teodora Safiye*; Medo Gutić; Ardea Milidrag; AzraGutić Cikotić; Ana Ravić Nikolić; Branimir Radmanović; Maja Lačković

Alzheimer’s disease is the most common type of dementia, a progressive neurological disorder that belongs to the primary degenerative dementias. Alzheimer’s disease is the most common cause of dementia (as many as 60-80% of cases) in people over 65 years of age, and is a continuous decline in thinking, behavioral and social skills that affects a person’s ability to function independently...


MedDocs Publishers

We always work towards offering the best to you. For any queries, please feel free to get in touch with us. Also you may post your valuable feedback after reading our journals, ebooks and after visiting our conferences.