IMPACT FACTOR: 1.8
Despite advancements in screening, diagnosis, and treatment approaches, Colorectal Cancer (CRC) is one of the most common cancers diagnosed globally and continues to be a major cause of cancer-related mortality, contributing significantly to the global disease burden [1-3]. Due to aggressive ...
Spray drying technology has been used extensively for converting highly crystalline and high melting molecules to Amorphous Solid Dispersions (ASD) to overcome the solubility and bioavailability challenges [1].
Zinc oxide nanoparticles (ZnO-NPs) are being widely studied for biological applications due to their adjustable physicochemical characteristics and possible antibacterial and anticancer effects. However, variable toxicity results and unsolved biosafety issues preclude their clinical use.
Proteolysis Targeting Chimeras (PROTACs) discovered over 20 years ago, have been classified as molecules beyond rule of five (bRoF), meaning they do not follow the classic Lipinski’s rule of five for solubility and bioavailability [1].
Chitosan, a natural biopolymer obtained through the deacetylation of chitin, has gained significant attention due to its biodegradability, safety, and multifunctional biological properties.
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