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Proteolysis Targeting Chimeras (PROTACs) discovered over 20 years ago, have been classified as molecules beyond rule of five (bRoF), meaning they do not follow the classic Lipinski’s rule of five for solubility and bioavailability [1].
Chitosan, a natural biopolymer obtained through the deacetylation of chitin, has gained significant attention due to its biodegradability, safety, and multifunctional biological properties.
As more new chemical entities are discovered with poor solubility and bioavailability, the applications of novel excipients and delivery technologies and their mechanisms by which the drug molecules are absorbed into systemic circulation, have been subject of continued interest [1].
Green synthesis of Selenium Nanoparticles (Se-NPs) harnesses plant resources to enhance therapeutic efficacy sustainably. Selenium Nanoparticles (Se-NPs) are known for their antioxidant, anti-inflammatory, and antidiabetic properties, making them promising candidates for addressing oxidative stress-related disorders
Folic Acid (FA) is introducing itself as a useful addition to wound management protocol. Herein, we report a novel eco-friendly method to prepare silver nanoparticles (AgNPs) using the anabolic FA as a reducing agent. The synthesis of FA-stabilized AgNPs (FA-AgNPs) was confirmed by spectrophotometric analysis, revealing the presence of the characteristic absorption peak corresponding to the Surface Plasmon Resonance of colloidal FA-AgNPs.
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