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Exploring the Genomic Landscape and Therapeutic Targets of Metastatic/Recurrent Cervical Cancer Based on Deep Analysis of Large Panel Genes

Yukai Zhu; Lei Wang; Fujun Jin; Dongling Zou; I Zhou; Xingtao Long

    Cervical cancer remains a leading cause of cancer-related mortality among women globally, with a disproportionate burden in regions lacking adequate screening and vaccination programs [1]. China faces particularly alarming ...


Fertility Preserving Management of Grade 2 Endometrial

Qais Shatnawi*; Bayan Maraqa; Dina Braik; Isam Lataifeh

    Endometrial cancer, although typically diagnosed in postmenopausal women, can rarely affect younger individuals, presenting a unique challenge when fertility preservation is desired. Studies have shown that oral progestin and progestin-releasing Intrauterine Devices (IUDs)...


Novel Classification of Ovarian Cancer Based on Transcription Factors That Are Closely Associated with Ovarian Development, Differentiation, and Growth

Mitsumasa Osakabe; Noriyuki Yamada; Hiroaki Itamochi; Tsukasa Baba; Noaki Yanagawa; Tamotsu Sugai*

    The traditional classification of Ovarian Cancer (OC), which includes High-Grade Serous Carcinoma (HGSC), Endometrioid Carcinoma (EC), Clear Cell Carcinoma (CCC), and Mucinous Carcinoma (MC), has been used worldwide....


Staged Procedure with Temporary Abdominal Closure in Gynaecologic-Oncology Patients in Prevention of Abdominal Compartment Syndrome: A Lesson to be Learnt

Monica Shi Qi Chua*; Ravichandran Nadarajah

    Abdominal Compartment Syndrome (ACS) is a medical emergency-characterized by organ dysfunction which is caused by intra-abdominal hypertension. Clinical signs are often non-specific and it is associated with high rate of mortality and morbidity when it is not recognized and managed promptly. Although ACS has not been commonly observed in gynaecological patients, it remains a potential risk especially in gynaecologic-oncology patients – many of whom will require extensive debulking surgery...


Gynecologic Cancer: Types, Causes and Therapeutic Approaches

Sadiya Zaki; Sibi G*

    Inflammatory ovarian masses may be difficult to distinguish preoperatively from ovarian malignancies. We present a case of a 54-year old woman with an ovarian mass, diagnosed during a COVID 19-infection. She underwent surgery because of pain and a challenging differential diagnosis on imaging. The frozen section was inconclusive and the final pathological examination showed no malignancy but only an inflammatory mass.


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